On midcycle, peripheral androstenedione and you may testosterone boost from the fifteen–20%. 37 There are several speculations concerning your character of your midcycle upsurge in androgens. It helps accelerate follicular atresia in order for during the ovulation, there can be an individual prominent follicle. 38 It could be involved in the stimulation away from sexual desire: it has been revealed you to females-initiated sexual activity takes place usually during the midcycle. 39

The rise inside the midcycle free testosterone and you can androstenedione observed in young female has been discovered getting smaller-to-missing during the more mature ladies (43–47 many years) who were bicycling continuously along with normal quantities of prolactin and thyroid-exciting hormonal.

Once the transform was indeed determined by period stage, it actually was determined that an enthusiastic ovarian, not an adrenal, techniques try involved. 38

The brand new diminished concentrations away from 100 % free testosterone and you can androstenedione, in place of high alterations in sex hormones-binding globulin, advise that inside the elderly women these types of hormones were created during the shorter amounts

Aromatization off androgens, which occurs generally inside extrasplanchnic structure, was firmly influenced by ages. Leia mais